The ability to combine genetic and biochemical analysis is a crucial step in untangling complex biological systems, yet few have matched David Engelkes success in orienting his research in this direction. Professor Engelkes research examines DNA and RNA recognition in higher organisms, and it focuses mainly on two important aspects of how cells appropriately express genetic information. His recent discovery of promoter interferencethat expression of one gene can block expression of neighboring genesis a fascinating observation that will undoubtedly lead to further excitement among the scientific community and perhaps contribute to gene therapy in the battle against cancer or viral infections such as AIDS.
Despite the multifaceted demands of his research program, David Engelke has remained a committed teacher and mentor, and his broad interests have led to several collaborative projects that have benefited the larger research community at Michigan. Acknowledged as a major resource, Professor Engelke is generous with his time, intellect, and materials. He helped to initiate the Universitys Human Genome Center, and is currently a co-director for the cooperative AIDS project. For the last six years, he has headed a course on the biochemistry of nucleic acids and gene expression, one of the largest and most popular courses in the Medical School.
For his excellence in research and teaching, outstanding student mentorship, superb collegial interactions, and unselfish service to the Department of Biological Chemistry and the University of Michigan, we are pleased to honor David Engelke with the Faculty Recognition Award.